The red cell adenylate kinase (AK) phenotype was determined by starch gel electrophoresis in 96 adult Caucasian subjects with affective disorders (24 with bipolar illness and 72 with unipolar illness). The phenotype frequencies and the gene frequencies of the bipolar group closely resembled that of
No association of red cell adenylate kinase phenotypes with affective disorders
β Scribed by G. Beckman; L. Beckman; C. Perris; E. Strandman
- Book ID
- 104704638
- Publisher
- Springer
- Year
- 1978
- Tongue
- English
- Weight
- 139 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0340-6717
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β¦ Synopsis
Red cell adenylate kinase (AK) phenotypes were studies in 195 patients with affective disorders (41 with the bipolar and 81 with the unipolar form of the disease) and 418 controls. No significant differences were found between patients and controls and between patients with different types of affective disorders. Thus the previous observation by Rundle et al. (1977) showing an increased frequency of the AK2 allele in the unipolar group was not confirmed.
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