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No association between the alpha-2 macroglobulin I1000V polymorphism and Alzheimer's disease

✍ Scribed by Fabienne Wavrant-DeVrièze; Varuni Rudrasingham; Jean-Charles Lambert; Sumi Chakraverty; Patrick Kehoe; Richard Crook; Philippe Amouyel; William Wu; Peter Holmans; Francis Rice; Jordi Pérez-Tur; Bernard Frigard; John C Morris; Stephanie Carty; Dominique Cottel; Nigel Tunstall; Simon Lovestone; Ronald C Petersen; Marie-Christine Chartier-Harlin; Alison Goate; Michael J Owen; Julie Williams; John Hardy


Book ID
117477426
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
57 KB
Volume
262
Category
Article
ISSN
0304-3940

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✍ Kim, K.W.; Jhoo, J.H.; Lee, K.U.; Lee, D.Y.; Lee, J.H.; Youn, J.Y.; Lee, B.J.; H 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 19 KB 👁 3 views

To examine the possible involvement of the alpha-1-antichymotrypsin gene (ACT) polymorphism in the manifestation of Alzheimer's disease (AD), we analyzed genotypes of the ACT and apolipoprotein E gene (APOE) among 110 Korean patients with probable AD and 209 nondemented controls. No significant diff