Dopamine β€-hydroxylase (DBH), the enzyme that converts dopamine to norepinepherine, has been proposed as being involved in the aetiology of schizophrenia. Previous work identified a functional polymorphism at nucleotide 910 of the DBH gene that results in a codon change in the mature protein Ala304S
β¦ LIBER β¦
No association between schizophrenia and polymorphisms within the genes for debrisoquine 4-hydroxylase (CYP2D6) and the dopamine transporter (DAT)
β Scribed by Daniels, J. ;Williams, J. ;Asherson, P. ;McGuffin, P. ;Owen, M.
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 312 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0148-7299
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## Abstract Alterations in dopaminergic system have been implicated in the pathophysiology of this disease for many years, and this study was performed to assess the possible involvement of the dopamine D4 receptor (__DRD4__) gene polymorphisms either in the 5β² upstream or in the coding regions, in