No association between RFLPs at the porphobilinogen deaminase gene and schizophrenia

✍ Scribed by M. J. Owen; R. Mant; E. Parfitt; J. Williams; P. Asherson; G. O'Mahoney; J. Os; D. Llewellyn; D. Collier; M. Gill; P. McGuffin

• Book ID: 104666249
• Publisher: Springer
• Year: 1992
• Tongue: English
• Weight: 227 KB
• Volume: 90
• Category: Article
• ISSN: 0340-6717
• DOI: 10.1007/bf00210756

✦ Synopsis

An association study of restriction fragment length polymorphisms (RFLPs) in the porphobilinogen deaminase (PBGD) gene and schizophrenia was conducted. RFLPs detected by MspI, PstI, ApaLI and BstNI in intron 1 of the gene were studied in 49 patients and 79 controls. There were no significant differences between the groups in allele frequencies, genotype counts or haplotype distribution.