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No Association between Parkinson's Disease and Low-Activity Alleles of CatecholO-Methyltransferase

✍ Scribed by Farzana Hoda; David Nicholl; Philip Bennett; Maria Arranz; Katherine J. Aitchison; Ammar Al-Chalabi; Hiroshi Kunugi; Homero Vallada; P.Nigel Leigh; K.Ray Chaudhuri; David A. Collier


Book ID
115579390
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
67 KB
Volume
228
Category
Article
ISSN
0006-291X

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Allelic association between the DRD2 Taq
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Genes encoding proteins involved in dopaminergic transmission have been of special interest during the evaluation of candidate genes for Parkinson's disease (PD). The dopamine D2 receptor gene (DRD2) is located on chromosome 11 q22-q23, and several polymorphisms of the gene have been described. The