NO activation of fos promoter elements requires nuclear translocation of G-kinase I and CREB phosphorylation but is independent of MAP kinase activation

Basal and Src kinase-mediated activation

Basal and Src kinase-mediated activation of the EphA2 promoter requires a cAMP-responsive element but is CREB-independent

✍ Xiaojian Du; Cindy Baldwin; Erika Hooker; Pauline Glorion; Serge Lemay 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 641 KB

## Abstract We have previously identified the EphA2 receptor tyrosine kinase as a potentially important injury‐responsive gene and a transcriptional target of Src kinase activity in renal ischemia‐reperfusion injury (IRI). In the present study, we confirmed, using EphA2 gene trap mice that the endo