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N/N/O versus N/O/O and N/O amino isoborneols in the enantioselective ethylation of benzaldehyde

✍ Scribed by Tomás de las Casas Engel; Beatriz Lora Maroto; Antonio García Martínez; Santiago de la Moya Cerero


Book ID
108284307
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
128 KB
Volume
19
Category
Article
ISSN
0957-4166

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Enantioselective synthesis of N,O-psicon
✍ Ugo Chiacchio; Luisa Borrello; Daniela Iannazzo; Pedro Merino; Anna Piperno; Ant 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 175 KB

The first enantioselective synthesis of b-D and b-L N,O-psiconucleosides is reported. The synthetic approach is based on the asymmetric 1,3-dipolar cycloaddition of the C-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]-N-methyl nitrone with ethyl 2-acetyloxyacrylate followed by Vorbru ¨ggen nucleosidation, an