✦ LIBER ✦

N,N -Dimethylsphingosine Inhibition of Sphingosine Kinase and Sphingosine 1-Phosphate Activity in Human Platelets †

✍ Scribed by Yatomi, Yutaka; Ruan, Fuqiang; Megidish, Tamar; Toyokuni, Tatsushi; Hakomori, Sen-itiroh; Igarashi, Yasuyuki

Book ID: 121233255
Publisher: American Chemical Society
Year: 1996
Tongue: English
Weight: 517 KB
Volume: 35
Category: Article
ISSN: 0006-2960
DOI: 10.1021/bi9515533

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Protein kinase C and platelet inhibition

Protein kinase C and platelet inhibition by D-erythro-sphingosine: Comparison with N,N-dimethylsphingosine and commercial preparation

✍ Wasiuddin A. Khan; Rick Dobrowsky; Samia El Touny; Yusuf A. Hannun 📂 Article 📅 1990 🏛 Elsevier Science 🌐 English ⚖ 577 KB

N , N -Dimethylsphingosine Is a Potent C

N , N -Dimethylsphingosine Is a Potent Competitive Inhibitor of Sphingosine Kinase but Not of Protein Kinase C: Modulation of Cellular Levels of Sphingosine 1-Phosphate and Ceramide †

✍ Edsall, Lisa C.; Van Brocklyn, James R.; Cuvillier, Olivier; Kleuser, Burkhard; 📂 Article 📅 1998 🏛 American Chemical Society 🌐 English ⚖ 261 KB

[Methods in Molecular Biology] Sphingosi

[Methods in Molecular Biology] Sphingosine-1-Phosphate Volume 874 || Immunohistochemical Detection of Sphingosine-1-Phosphate and Sphingosine Kinase-1 in Human Tissue Samples

✍ Pébay, Alice; Turksen, Kursad 📂 Article 📅 2012 🏛 Humana Press ⚖ 408 KB

Activation of Protein-Tyrosine Kinase Sy

Activation of Protein-Tyrosine Kinase Syk in Human Platelets Stimulated with Lysophosphatidic Acid or Sphingosine 1-Phosphate

✍ Libo Yang; Yutaka Yatomi; Nobuo Hisano; Ruomei Qi; Naoki Asazuma; Kaneo Satoh; Y 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 87 KB

Role of sphingosine kinase 1 and sphingo

Role of sphingosine kinase 1 and sphingosine-1-phosphate in CD40 signaling and IgE class switching

✍ Kim, E. Y.; Sturgill, J. L.; Hait, N. C.; Avni, D.; Valencia, E. C.; Maceyka, M. 📂 Article 📅 2014 🏛 The Federation of American Societies for Experimen 🌐 English ⚖ 846 KB

Dimethylsphingosine and FTY720 inhibit t

Dimethylsphingosine and FTY720 inhibit the SK1 form but activate the SK2 form of sphingosine kinase from rat heart

✍ Donald A. Vessey; Michael Kelley; Jianqing Zhang; Luyi Li; Rong Tao; Joel S. Kar 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 313 KB

## Abstract Fractionation of cytosolic sphingosine kinase (SKase) activity by gel filtration chromatography gave rise to a 96‐kDa peak that contained only the SK2 form of SKase (by Western analysis) and a broad ca. 46 kDa peak that contained only SK1 forms. SK2 appeared to have a bound accessory pr