NMR studies on 1,2-dihydro-2-(4-aminophenyl)-4-[4-(4-aminophenoxy)-4-phenyl]-(2H)phthalazin-1-one

✍ Scribed by Tianzhi Wang; Lin Cheng; Tao Zhang; Hanzhen Yuan; Shizhen Mao

• Publisher: John Wiley and Sons
• Year: 2002
• Tongue: English
• Weight: 101 KB
• Volume: 40
• Category: Article
• ISSN: 0749-1581
• DOI: 10.1002/mrc.1087

✦ Synopsis

Abstract

An unsymmetrical heterocyclic diamine, 1,2‐dihydro‐2‐(4‐aminophenyl)‐4‐[4‐(4‐aminophenoxy)‐4‐phenyl]‐(2__H__)phthalazin‐1‐one, was synthesized. Its ^1^H and ^13^C NMR spectra were completely assigned by utilizing the two‐dimensional heteronuclear ^13^C–^1^H multiple‐bond coherence (HMBC) spectroscopy, and heteronuclear ^13^C–^1^H one‐bond correlation spectroscopy, homonuclear shift correlation spectroscopy (H,H‐COSY) and rotating frame Overhauser enhancement spectroscopy (ROESY). The structure of the compound was shown to be the phthalazinone rather than the phthalazine ether from cross peaks and chemical shifts of the protons. Copyright © 2002 John Wiley & Sons, Ltd.