NMR studies of the interactions of neutral polymers with unilamellar vesicles

✍ Scribed by Réjean Labonté; Zhisheng Gao; Jan C.T. Kwak

• Book ID: 103966865
• Publisher: Elsevier Science
• Year: 1993
• Tongue: English
• Weight: 395 KB
• Volume: 78
• Category: Article
• ISSN: 0927-7757
• DOI: 10.1016/0927-7757(93)80332-9

✦ Synopsis

The NMR paramagnetic relaxation method is used to investigate the interactions between poly(ethylene oxide) (PEO) and poly(propylene oxide) (PPO) and small unilamellar vesicles (SUVs) of phospholipids.

The results indicate the PEO does not interact with phospholipid vesicles; it is located exclusively in the bulk water phase. Low molecular weight PPO polymers distribute between the aqueous and lipid phases. The vesicles remain impermeable to Pr3+ ions when PEO or PPO is present.