NMR Studies of the FK506 Binding-Protein Bound to a Spin-Labeled Ascomycin Analog

1H, 13C, and 15N assignments and seconda

1H, 13C, and 15N assignments and secondary structure of the FK506 binding protein when bound to ascomycin

✍ Robert X. Xu; David Nettesheim; Edward T. Olejniczak; Robert Meadows; Gerd Gemme 📂 Article 📅 1993 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 998 KB

## Abstract The ^1^H, ^13^C, and ^15^N resonances of FKBP when bound to the immunosuppressant, ascomycin, were assigned using a computer‐aided analysis of heteronuclear double and triple resonance three‐dimensional nmr spectra of [U‐^15^N] FKBP/ascomycin and [U‐^15^N, ^13^C] FKBP/ascomycin. In addi