2D NMR spectroscopy and J coupling constant analysis are applied to resolve the structure of two photoproducts of thymidylyl-(3'----5')-thymidine. These products are cyclobutane type thymine dimers possessing the cis-syn (the predominant one) and trans-syn geometry. The cis-syn is formed in an ANTI-
NMR studies of bipyrimidine cyclobutane photodimers
β Scribed by Thea M. G. KONING; Jeroen J. G. van SOEST; Robert KAPTEIN
- Book ID
- 115128324
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 999 KB
- Volume
- 195
- Category
- Article
- ISSN
- 1432-1327
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π SIMILAR VOLUMES
Both trans-syn cyclobutane-type photodimers of 2Π-deoxyuridylyl (3Π-5Π) thymidine (dUpdT) were formed by deamination of the corresponding trans-syn cyclobutane photodimers of 2Π-deoxycytidylyl (3Π-5Π) thymidine (dCpdT) and were examined by 1 H-, 13 C-, and 31 P-nmr spectroscopy. One-and two-dimensio
The recent cownunication of Blackburn and Davies1 prwpts us to report our results on the photodimer of thymine (I), obtained2 by irradiation of frozen aqueous solutions of thymine. The work described in this paper gives independent confirmation to the head-to-head cis cyclobutane structure,for I, pr
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