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NMR Structural Determinants of Eosinophil Cationic Protein Binding to Membrane and Heparin Mimetics

✍ Scribed by García-Mayoral, María Flor; Moussaoui, Mohammed; de la Torre, Beatriz G.; Andreu, David; Boix, Ester; Nogués, M. Victòria; Rico, Manuel; Laurents, Douglas V.; Bruix, Marta

Book ID
119207205
Publisher
Biophysical Society
Year
2010
Tongue
English
Weight
915 KB
Volume
98
Category
Article
ISSN
0006-3495

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Structure and dynamics of cationic membr
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## Abstract Many membrane peptides and protein domains contain functionally important cationic Arg and Lys residues, whose insertion into the hydrophobic interior of the lipid bilayer encounters significant energy barriers. To understand how these cationic molecules overcome the free energy barrier