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NMR Structural Characterization and Computational Predictions of the Major Intermediate in Oxidative Folding of Leech Carboxypeptidase Inhibitor

✍ Scribed by Joan L. Arolas; Loyola D’Silva; Grzegorz M. Popowicz; Francesc X. Aviles; Tad A. Holak; Salvador Ventura


Book ID
113918479
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
436 KB
Volume
13
Category
Article
ISSN
0969-2126

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## Abstract The three disulfide __Ecballium elaterium__ trypsin inhibitor II (EETI II) reduction with dithiothreitol (DTT) and re‐oxidation of the fully reduced derivative have been examined. A common stable intermediate has been observed for both processes. Isolation and sequencing of carboxymethy