Although the measurement of the pH of biological systems using the 31P NMR response of inorganic phosphate is well known, sometimes in blood absolute determination of the intensity and position of the Pi resonance is precluded by overlap from the doublet resonance of 2,3-diphosphoglycerate. Three te
NMR Spectroscopy with Spectral Editing for the Analysis of Complex Mixtures
β Scribed by Dixon, Ann M.; Larive, Cynthia K.
- Book ID
- 115364253
- Publisher
- Society for Applied Spectroscopy
- Year
- 1999
- Tongue
- English
- Weight
- 551 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0003-7028
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## Abstract Unambiguous identification of individual metabolites present in complex mixtures such as biofluids constitutes a crucial prerequisite for quantitative metabolomics, toward better understanding of biochemical processes in living systems. Increasing the dimensionality of a given NMR corre
This work was supported by National Science Foundation Grant CHE8921144. We thank Professor J. R. Norris and Dr. J. Tang for providing LPZOOM software and Dr. S. J. Gibbs for help with programming and instrumentation.
## Abstract Quantification of the excitatory amino acid of glutamine and glutamate is extremely important partly because, when in excessive amounts, they can produce neuronal damage. However, quantification of such metabolites seems to be not straightforward owing to a large number of metabolic sig