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NMR solution structure and function of the C-terminal domain of eukaryotic class 1 polypeptide chain release factor

✍ Scribed by Alexey B. Mantsyzov; Elena V. Ivanova; Berry Birdsall; Elena Z. Alkalaeva; Polina N. Kryuchkova; Geoff Kelly; Ludmila Y. Frolova; Vladimir I. Polshakov


Book ID
111313523
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
993 KB
Volume
277
Category
Article
ISSN
1432-1327

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The structure of the C-terminal DNA-binding domain of human immunovirus-1 integrase has been refined using nuclear magnetic resonance spectroscopy. The protein is a dimer in solution and shows a well-defined dimer interface. The folding topology of the monomer consists of a fivestranded ␀-barrel tha