NMR proof of a piperidine to pyrrolidine ring contraction during nucleophilic substitution

✍ Scribed by Gabrijela Ambrožič; Simon Čeh; Andrej Petrič

• Publisher: John Wiley and Sons
• Year: 1998
• Tongue: English
• Weight: 193 KB
• Volume: 36
• Category: Article
• ISSN: 0749-1581
• DOI: 10.1002/(sici)1097-458x(1998110)36:11<873::aid-omr375>3.0.co;2-b

✦ Synopsis

decan-4-one, at room and elevated temperatures were compared and the respective structure were assigned based on 1H and 13C NMR spectra. Piperidine to pyrrolidine ring transformation at elevated temperature is documented.