NMR Methods for Optical Purity Determination of Pharmaceuticals
โ Scribed by Aboul-enein, Hassan Y.
- Book ID
- 118270280
- Publisher
- Taylor and Francis Group
- Year
- 1988
- Tongue
- English
- Weight
- 321 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0003-2719
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Determining the enantiomeric purity of chiral therapeutic agents is important in the development of active pharmaceutical ingredients (API). A strategy for determining the enantiomeric purity of three APIs was developed using nuclear magnetic resonance (NMR) and the chiral solvating age
## Abstract A novel and very accurate method was established for the determination of the optical purity of a peptide by use of the following procedure: (1) hydrolysis of the peptide in deuterium chloride, (2) gas chromatographic separation of each amino acid enantiomer on a chiral phase, and (3) d