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NMR Investigation of the Binding between Human Profilin I and Inositol 1,4,5-Triphosphate, the Soluble Headgroup of Phosphatidylinositol 4,5-Bisphosphate †

✍ Scribed by Richer, Sarah M.; Stewart, Nichole K.; Tomaszewski, John W.; Stone, Martin J.; Oakley, Martha G.


Book ID
120595861
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
743 KB
Volume
47
Category
Article
ISSN
0006-2960

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Profilactin, the profi1in:actin complex, which is present in large amounts in extracts of many types of eukaryotic cells, appears to serve as the precursor of microfilaments. It was reported recently that profilactin interacts specifically with phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)Pz) (