NMR Evidence for Major Groove Binding of Both Λ- and Δ-[Ru(bpy)2(pqx)](PF6)2 to the Oligonucleotide d(CGCGAATTCGCG)2

Synthesis and Characterization of the Di

Synthesis and Characterization of the Diastereomers Λ- and Δ-[Ru(bpy)2(m-bpy-Gly-L-His-L-Lys)]Cl2 − 1H NMR Studies on Their Interactions with the Deoxynucleotide Duplex d[(5′-CGCGAATTCGCG-3′)2]

✍ Alexandra Myari; Nick Hadjiliadis; Achilleas Garoufis 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 267 KB 👁 1 views

## Abstract The synthesis and characterization of the diastereomeric complexes Λ‐ and Δ‐[Ru(bpy)~2~(m‐bpy‐GHK)]Cl~2~, (GHK = glycine‐L‐histidine‐L‐lysine, m‐bpy = 4′‐methyl‐2,2′‐bipyridine) as well as their binding properties to the deoxynucleotide duplex d(5′‐CGCGAATTCGCG‐3′)~2~ studied by means o