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NMR assignment of the phosphotyrosine binding (PTB) domain of tensin

✍ Scribed by Marilisa Leone; Eric Chi-Wang Yu; Robert Liddington; Maurizio Pellecchia

Publisher: Springer Netherlands
Year: 2006
Tongue: English
Weight: 128 KB
Volume: 36
Category: Article
ISSN: 0925-2738
DOI: 10.1007/s10858-006-9011-3

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## Abstract Tensin is a protein confined at those discrete and specialized regions of the plasma membrane, known as focal adhesions. It contains, at the C‐terminus, a phosphotyrosine binding (PTB) domain that can interact with the cytoplasmic tail of β‐integrins and is necessary for localization of

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