𝔖 Bobbio Scriptorium
✦   LIBER   ✦

NMR and X-ray structural studies on 3-benzyl-8-bromoadenine

✍ Scribed by Huey-San Melanie Siah; Carl Henrik Görbitz; Lise-Lotte Gundersen

Publisher
Journal of Heterocyclic Chemistry
Year
2011
Tongue
English
Weight
305 KB
Volume
48
Category
Article
ISSN
0022-152X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

8‐Bromoadenine was benzylated in the presence of base to give a mixture of two regioisomers. One was easily recognized as 9‐benzyl‐8‐bromoadenine, but the other structure could not be determined with absolute certainty by NMR. Therefore, X‐ray crystallography was used to prove that the benzyl group was attached to N‐3. Furthermore, it is shown that the 3‐benzyl adenine derivative exists as the amine tautomer both in the crystalline state as well as in solution (DMSO‐d~6~), with restricted rotation around the N^6^C6 bond. J. Heterocyclic Chem., (2011).

📜 SIMILAR VOLUMES

Solution NMR and X-Ray Structural Studie
Solution NMR and X-Ray Structural Studies on Phthalocyaninatoiron Complexes
✍ Ignacio Fernández; Paul S. Pregosin; Alberto Albinati; Silvia Rizzato; Ursula E. 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 German ⚖ 227 KB

## Abstract The addition of primary amines as solubilizing reagents for phthalocyaninatoiron complexes is shown to afford six‐coordinate bis(amine)phthalocyaninato complexes, __i.e.__, [Fe(amine)~2~(pc)] **2** (amine = decan‐1‐amine) and **3** (amine = benzylamine), with the two new N‐donors occupy