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NMDA Receptor Subunits Have Differential Roles in Mediating Excitotoxic Neuronal Death Both In Vitro and In Vivo

โœ Scribed by Liu, Y.; Wong, T. P.; Aarts, M.; Rooyakkers, A.; Liu, L.; Lai, T. W.; Wu, D. C.; Lu, J.; Tymianski, M.; Craig, A. M.; Wang, Y. T.


Book ID
118035720
Publisher
Society for Neuroscience
Year
2007
Tongue
English
Weight
408 KB
Volume
27
Category
Article
ISSN
0270-6474

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## Abstract Early overstimulation of ionotropic glutamate receptors (iGluRs), such as the __N__โ€methylโ€Dโ€aspartate (NMDA) and ฮฑโ€aminoโ€3โ€hydroxyโ€5โ€methylisoxazoleโ€4โ€propionate (AMPA) receptors, produces excitotoxicity in several brain regions. The molecular composition of those receptors and their r