NMDA receptor dependent paroxysmal discharges in the dentate gyrus
β Scribed by Stringer, Janet L.; Lothman, Eric W.
- Book ID
- 122746215
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 409 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0304-3940
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Research has demonstrated environmentally induced plasticity of hippocampal dentate gyrusevoked potentials. Other research has shown a role of the NMDA receptor in dentate gyrus long-term potentiation (LTP). The authors tested the role of the NMDA receptor in one form of environmentally induced plas
## Abstract This report examines the inductive mechanism involved in longβterm heterosynaptic depression (LTD) in the dentate gyrus of anaesthetized rats. Associative and nonβassociative stimulus protocols were implemented, using the ipsilateral medial and lateral perforant path inputs to the denta