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NMDA and Non-NMDA Receptor-Mediated Excitotoxicity Are Potentiated in Cultured Striatal Neurons by Prior Chronic Depolarization

✍ Scribed by Quan Chen; D.James Surmeier; Anton Reiner


Book ID
115607032
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
191 KB
Volume
159
Category
Article
ISSN
0014-4886

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Paroxysmal long-lasting depolarizations
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## Abstract In primary cultures of hippocampal neurons from the embryonic rat, spontaneous depolarizations lasting up to 6 sec adn resembling paroxysmal depolarization shifts (PDAs) appeared after 11 day7s in vitro. These depolarizations are presumably generated by sy6naptic events, because: (1) bo