✦ LIBER ✦

nm23-H1 protein immunoreactivity in laryngeal carcinoma

✍ Scribed by C. Soon Lee; Anna Redshaw; Guy Boag

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 520 KB
Volume: 77
Category: Article
ISSN: 0008-543X
DOI: 10.1002/(sici)1097-0142(19960601)77:11<2246::aid-cncr10>3.0.co;2-x

No coin nor oath required. For personal study only.

✦ Synopsis

The nm23-H1 gene encodes a 17-kilodalton cytoplasmic and nuclear protein that has recently been shown to be reduced in a number of human carcinomas including breast, colorectal, lung, gallbladder, and biliary tract carcinomas. This study examines the immunohistochemical staining characteristics of the nm23-H1 protein in human laryngeal carcinomas and nonneoplastic laryngeal polyps, and attempts to determine if there is any relationship between reduction of nm23-H1 protein immunoreactivity and prognosis of patients with laryngeal carcinoma.

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