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NM 283 has potent antiviral activity against genotype 1 chronic hepatitis C virus (HCV-1) infection in the chimpanzee

✍ Scribed by D.N. Standring; R. Lanford; T. Wright; R.T. Chung; V. Bichko; E. Cretton-Scott; X. Pan-Zhou; S. Bergelson; L. Qu; M. Tausek; E. Bridges; A. Moussa; R. Storer; C. Pierra; S. Benzaria; G. Gosselin; P. La Colla; J.P. Sommadossi


Book ID
117372343
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
145 KB
Volume
38
Category
Article
ISSN
0168-8278

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✍ Frank Wagner; Robert Thompson; Constantino Kantaridis; Paul Simpson; Philip J. F πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 599 KB

More effective and better-tolerated therapies are needed for chronic hepatitis C virus (HCV) infection. Among the direct-acting anti-HCV agents in development is the nonstructural 5B protein (NS5B polymerase) non-nucleoside inhibitor filibuvir. We investigated the antiviral activity, pharmacokinetic