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NKT cell–mediated repression of tumor immunosurveillance by IL-13 and the IL-4R–STAT6 pathway

✍ Scribed by Terabe, Masaki; Matsui, So; Noben-Trauth, Nancy; Chen, Hangjiong; Watson, Cynthia; Donaldson, Debra D.; Carbone, David P.; Paul, William E.; Berzofsky, Jay A.


Book ID
109829626
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
247 KB
Volume
1
Category
Article
ISSN
1529-2908

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We have previously observed a novel role of natural killer T (NKT) cells in negative regulation of antitumor immune responses against an immunogenic regressor tumor expressing a transfected viral antigen. Here, we investigated whether hidden spontaneous antitumor immunosurveillance, in the absence o