NK1.1 Cells Express 4-1BB (CDw137) Costimulatory Molecule and Are Required for Tumor Immunity Elicited by Anti-4-1BB Monoclonal Antibodies
✍ Scribed by Ignacio Melero; Janet V. Johnston; Walter W. Shufford; Robert S. Mittler; Lieping Chen
- Book ID
- 112240024
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 623 KB
- Volume
- 190
- Category
- Article
- ISSN
- 0008-8749
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Tumor cells express tumor‐associated antigens (TAAs), which can serve as targets for the immune system. However, the majority of TAAs are overexpressed products of normal cellular genes; as such, self‐tolerance mechanisms have hindered their use for the induction of effective antitumor
## Abstract Human telomerase reverse transcriptase (hTERT) represents an attractive target for cancer immunotherapy because hTERT is reactivated in most human tumors. In an attempt to develop an effective vaccine against most human cancers, we constructed chemotactic‐hTERT vaccine. Two hTERT fragme