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NK cells enhance the induction of CTL responses by IL-15 monocyte-derived dendritic cells

✍ Scribed by Hardy, Melinda Y; Kassianos, Andrew J; Vulink, Annelie; Wilkinson, Ray; Jongbloed, Sarah L; Hart, Derek N J; Radford, Kristen J


Book ID
109864882
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
478 KB
Volume
87
Category
Article
ISSN
0818-9641

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## Abstract RNA interference technology has been used to modulate dendritic cell (DC) function by targeting the expression of genes such as IL‐12 and NF‐kB. In this paper, we demonstrate that transfectionof DC with IL‐10‐specific double strands of small interference RNA (siRNA) resulted in potent s