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NK cell-mediated killing of AML blasts: role of histamine, monocytes and reactive oxygen metabolites

✍ Scribed by M. Brune; M. Hansson; U.-H. Mellqvist; S. Hermodsson; K. Hellstrand

Book ID
114792159
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
607 KB
Volume
57
Category
Article
ISSN
0902-4441

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THE ROLE OF REACTIVE OXYGEN METABOLITES
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✍ THOMAS A. HOUZE; PER-ANDERS LARSSON; KRISTOFFER HELLSTRAND; BENGT GUSTAVSSON 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 284 KB

The secretion of interferon‐γ (IFN‐γ) by natural killer (NK) cells following __in vitro__ stimulation with interleukin‐2 (IL‐2) is inhibited by co‐incubation with autologous monocytes at a transcriptional level by more than sixty‐fold. In this study, we investigate the nature of the inhibitory signa