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Nivolumab and ipilimumab therapy for advanced melanoma

โœ Scribed by Burki, Talha Khan

Book ID
123187701
Publisher
The Lancet
Year
2013
Tongue
English
Weight
206 KB
Volume
14
Category
Article
ISSN
1470-2045

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Nivolumab plus Ipilimumab in Advanced Me
Nivolumab plus Ipilimumab in Advanced Melanoma
โœ Wolchok, Jedd D.; Kluger, Harriet; Callahan, Margaret K.; Postow, Michael A.; Ri ๐Ÿ“‚ Article ๐Ÿ“… 2013 ๐Ÿ› Massachusetts Medical Society ๐ŸŒ English โš– 646 KB
Nivolumab plus Ipilimumab in Advanced Me
Nivolumab plus Ipilimumab in Advanced Melanoma
โœ Wolchok, Jedd D.; Kluger, Harriet; Callahan, Margaret K.; Postow, Michael A.; Ri ๐Ÿ“‚ Article ๐Ÿ“… 2013 ๐Ÿ› Massachusetts Medical Society ๐ŸŒ English โš– 646 KB

## BACKGROUND In patients with melanoma, ipilimumab (an antibody against cytotoxic T-lymphocyteassociated antigen 4 [CTLA-4]) prolongs overall survival, and nivolumab (an antibody against the programmed death 1 [PD-1] receptor) produced durable tumor regression in a phase 1 trial. On the basis of t