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Nitrosation in vitro and in vivo by sodium nitrite, and mutagenicity of nitrogenous pesticides

✍ Scribed by J.P. Seiler


Book ID
113191175
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
1015 KB
Volume
48
Category
Article
ISSN
0027-5107

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Mutagenicity detection of in vivo nitros
✍ Whong, Wen-Zong ;Speciner, Norman D. ;Edwards, Gordon S. πŸ“‚ Article πŸ“… 1979 πŸ› Wiley (John Wiley & Sons) βš– 326 KB

In vivo nitrosation of dimethylamine by nitrite was measured with an intrahepatic host-mediated mutagenicity assay using Salmonella typhimurium as the detecting organism. It was possible to detect the product, N-nitrosodimethylamine, at much lower doses with this system than with previously reported