Mutagenicity detection of in vivo nitros
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Whong, Wen-Zong ;Speciner, Norman D. ;Edwards, Gordon S.
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Article
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1979
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Wiley (John Wiley & Sons)
β 326 KB
In vivo nitrosation of dimethylamine by nitrite was measured with an intrahepatic host-mediated mutagenicity assay using Salmonella typhimurium as the detecting organism. It was possible to detect the product, N-nitrosodimethylamine, at much lower doses with this system than with previously reported