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Nitrosation causes mitochondrial dysfunction and cytochrome c release in myocardium

✍ Scribed by Aiste Jekabsone; Vilmante Borutaite


Book ID
117142095
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
127 KB
Volume
34
Category
Article
ISSN
0022-2828

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A 3-month-old female infant had profound generalized weakness, de Toni-Fanconi-Debre syndrome, and lactic acidosis. She required assisted ventilation and died at the age of 8 months. Muscle biopsy showed accumulation of mitochondria, glycogen, and lipid droplets. Histochemical reaction and immunocyt