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Nitrosamine formation from interaction of isosorbide dinitrate and hydroxyzine HCl, a tertiary amine

โœ Scribed by Ilene H. Raisfeld; Clara Lin


Book ID
115774364
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
569 KB
Volume
28
Category
Article
ISSN
0006-2952

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Rapid nitrosamine formation from a terti
โœ R.N. Loeppky; J.R. Outram; W. Tomasik; J.M. Faulconer ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 267 KB

2-(N,N-Dimethylaminomethyl)pyrrole reacts instantaneously with nitrous acid at 25" to produce diemthylnitrosamine, maleimidemonooxine, formaldehyde and other products. The data implicate new mechanisms of tertiary amine nitrosation. N-Alkyl tertiary amines react very slowly at 25" with nitrous acid