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Nitrogen Heterocyclic Bases as Catalysts for the Selective Synthesis of Symmetric P,P′-Disubstituted Bisphosphonate Esters.

✍ Scribed by Dominique C. Stepinski; Jacob N. Hess; Albert W. Herlinger


Publisher
John Wiley and Sons
Year
2004
Weight
80 KB
Volume
35
Category
Article
ISSN
0931-7597

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Several new chiral auxiliaries with differing steric and electronic environments, such as ␣,␣Ј-dimethyl-2,6-pyridinedimethanol, ␣,␣Ј-ditrifluoromethyl-2,6pyridinedimethanol, ␣,␣Ј-dipentafluoroethyl-2,6-pyridinedimethanol, and ␣,␣Ј-diallyl-2,6pyridinedimethanol, have been examined and compared with ␣