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Nitro group participation in leuckart reaction-I

✍ Scribed by M. Srinivasan; J.B. Rampal


Book ID
104242891
Publisher
Elsevier Science
Year
1974
Tongue
French
Weight
123 KB
Volume
15
Category
Article
ISSN
0040-4039

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A rho value of +0.21 is reported for the reaction of mono 4-substitutad benzophenoneswith formamide. This, in conjunction with a kinetic isotope effect value of 1.80 obtained for the system, suggests a rate-limiting C-H bond cleavage. The Leuckart reaction, a process for the alkylation of ammonia o