Potential carcinostatics V. Synthesis an
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M. J. Wanner; E. M. van Wijk; G. J. Koomen; U. K. Pandit
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Article
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2010
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Elsevier Science
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English
⚖ 443 KB
## Abstract β,β‐Dimethylaspartic acid was obtained by the aluminium‐amalgam reduction of the __O__‐methyloxime of diethyl 2‐oxo‐3,3‐dimethyl‐1,4‐butanedioate and subsequent hydrolysis. The (latter) diester was conveniently prepared by the condensation of ethyl 2‐bromo‐2‐methylpropionate with diethy