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Nitrite administration ameliorates mitochondrial bioenergetics and is neuroprotective in cellular and vertebrate models of Parkinson’s disease

✍ Scribed by Milanese, Chiara; Gladwin, Mark; Mastroberardino, Pier G.


Book ID
123323142
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
57 KB
Volume
65
Category
Article
ISSN
0891-5849

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## Abstract Nicotinamide, the principal form of niacin (vitamin B3), has been proposed to be neuroprotective in Parkinson's disease. However, the effects and mechanisms of nicotinamide on motor function in animals and on mitochondrial function in cellular systems have not been well studied. We hypo