Nitrile addition to tricarbonylcyclohexadienylium complexes: The effect of perchlorate counteranion

✍ Scribed by Chi Wi Ong; Yen Kai Chao; You An Chang

• Book ID: 104214635
• Publisher: Elsevier Science
• Year: 1994
• Tongue: French
• Weight: 153 KB
• Volume: 35
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)73417-4

✦ Synopsis

The ability of cyclohexadienyliumiron complexes to undergo nucleophilic addition reactions have led to their wide application as key intermediates in synthesis. Unfortunately, the cyanide addition reaction has been hampered with severe limitations due to undesirable side reactions and low yield*. Stephenson2 has reported that the use of ThiS-CN with the presences of steric hinderance at the C-l terminus and deactivation by methoxy group also favors the formation of aromatized product. We have recently pinpointed the problem of