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Nitric oxide–forming reactions of the water-soluble nitric oxide spin-trapping agent, MGD

✍ Scribed by Koichiro Tsuchiya; Jin-Jie Jiang; Masanori Yoshizumi; Toshiaki Tamaki; Hitoshi Houchi; Kazuo Minakuchi; Kenji Fukuzawa; Ronald P. Mason


Book ID
114277625
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
285 KB
Volume
27
Category
Article
ISSN
0891-5849

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Nitric oxide synthase (NOS) generates nitric oxide (NO⅐) by the oxidation of L-arginine. Spin trapping in combination with electron paramagnetic resonance (EPR) spectroscopy using ferro-chelates is considered one of the best methods to detect NO⅐ in real time and at its site of generation. The spin