Nitric oxide synthase inhibitors improve
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Laura K. Knox; Alastair G. Stewart; Peter G. Hayward; Professor Wayne A. Morriso
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Article
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1994
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John Wiley and Sons
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English
β 343 KB
## Abstract The ability of nitric oxide (NO) synthase inhibitors to reduce ischemiaβinduced skin flap necrosis was assessed using a modified McFarlane flap in the rat. Flap survival was significantly improved in LβNIO treated (86 Β± 2%), LβNAMEβtreated (84 Β± 2%), and aminoguanidineβtreated (76 Β± 2%)