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Nitric Oxide Synthase Inhibition Delays Axonal Degeneration and Promotes the Survival of Axotomized Retinal Ganglion Cells

✍ Scribed by Paulo D. Koeberle; Alexander K. Ball


Book ID
115607012
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
943 KB
Volume
158
Category
Article
ISSN
0014-4886

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Adult rat retinal ganglion cells (RGC) undergo degeneration after optic nerve transection. Studies have shown that exogenously applied neurotrophic factors such as brain-derived neurotrophic factor (BDNF) can attenuate axotomy-induced as well as developmental RGC death. Here, we examined whether gli