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Nitric Oxide Synthase Inhibition by L-NAME Prevents Brain Acidosis During Focal Cerebral Ischemia in Rabbits

✍ Scribed by Regli, Luca; Held, Mark C.; Anderson, Robert E.; Meyer, Fredric B.

Book ID: 110078704
Publisher: Nature Publishing Group
Year: 1996
Tongue: English
Weight: 428 KB
Volume: 16
Category: Article
ISSN: 0271-678X
DOI: 10.1097/00004647-199609000-00024

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## Abstract Diffusion‐weighted MRI at 2 T was used to monitor and assess tissue damage after permanent middle cerebral artery occlusion (MCAO) in wild‐type (WT) and mice deficient in nitric oxide synthase gene expression (nNOS^−^). The ischemic lesion was evaluated 3 h after occlusion and subdivide