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Nitric oxide synthase inhibition by haem oxygenase decreases macrophage nitric-oxide-dependent cytotoxicity: a negative feedback mechanism for the regulation of nitric oxide production

✍ Scribed by V. Turcanu; M. Dhouib; P. Poindron


Book ID
117615007
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
394 KB
Volume
149
Category
Article
ISSN
0923-2494

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In mixed glial cell cultures from cerebral cortices of newborn rats, endotoxin induces inducible nitric oxide (iNOS), nitric oxide (NO), and interleukin-1 beta (IL-1 beta) production in microglial cells. Earlier we demonstrated that endotoxin induced iNOS but not IL-1 beta expression in microglial c