Catalysis by nitric oxide synthase
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Michael A Marletta; Amy R Hurshman; Kristin M Rusche
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Article
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1998
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Elsevier Science
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English
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The enzyme nitric oxide synthase catalyzes the oxidation of the amino acid L-arginine to L-citrulline and nitric oxide in an NADPH-dependent reaction. Nitric oxide plays a critical role in signal transduction pathways in the cardiovascular and nervous systems and is a key component of the cytostatic