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Nitric Oxide Scavenging by Red Blood Cell Microparticles

✍ Scribed by Liu, Chen; Zhao, Weixin; Christ, George J.; Kim Shapiro, Daniel B.

Book ID
121950818
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
189 KB
Volume
53
Category
Article
ISSN
0891-5849

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## Abstract The administration of extracellular, hemoglobin‐based oxygen carriers often elicits an acute increase in blood pressure by vasoconstriction. This side effect is now recognized to be due to the depletion of nitric oxide (endothelial‐derived relaxing factor) by the extravasuated hemoglobi