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Nitric oxide releases intracellular zinc from prokaryotic metallothionein in Escherichia coli

✍ Scribed by Marie R.B Binet; Hugo Cruz-Ramos; Jay Laver; Martin N Hughes; Robert K Poole


Book ID
111756376
Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
234 KB
Volume
213
Category
Article
ISSN
0378-1097

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✍ Latha M. Malaiyandi; Kirk E. Dineley; Ian J. Reynolds πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 128 KB

## Abstract Excessive accumulation of the heavy metal zinc is cytotoxic. As a consequence, cellular vulnerability to zinc‐induced injury may be regulated by the abundance of proteins that maintain intracellular free zinc concentrations ([Zn^2+^]~i~). In this study, we overexpressed the zinc‐binding