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Nitric oxide modulates the discharge rate of basal forebrain neurons

✍ Scribed by Andrey Kostin; Dag Stenberg; Anna V. Kalinchuk; Tarja Porkka-Heiskanen

Publisher
Springer
Year
2008
Tongue
English
Weight
625 KB
Volume
201
Category
Article
ISSN
0033-3158

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## Abstract Nitric oxide (^β€’^NO) is a labile endogenous free radical produced upon glutamatergic neuronal activity in hippocampus by neuronal nitric oxide synthase (nNOS), where it acts as a modulator of both synaptic plasticity and cell death associated with neurodegeneration. The low CNS levels a