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Nitric Oxide in Retina: Relation to Excitatory Amino Acids and Excitotoxicity

✍ Scribed by Gall D. Zeevalk; William J. Nicklas

Book ID
115604774
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
556 KB
Volume
58
Category
Article
ISSN
0014-4835

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Nitric oxide synthase (NOS) activity was determined in adult rat frontal cortex and hippocampus by measuring the conversion of L-[3H]arginine to L-[3H]citrulline. N-methyl-D-aspartate (NMDA), but not kainate or a-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA), stimulated NOS activity. This ef